Plague - Treatment for plague begins as soon as the health care provider suspects the disease. Treatment is typically done in the hospital. Antibiotics that may be used include the following: Gentamicin. Doxycycline (Monodox, Vibramycin, others). Ciprofloxacin (Cipro). Levofloxacin. Moxifloxacin (Avelox). Chloramphenicol.

 
Plague. Plague is an infectious disease of animals and humans caused by a bacterium named Yersinia pestis. People usually get plague from the bite of a rodent flea that is carrying plague bacteria or by handling an infected animal. Although plague is a rare disease, about half of US cases each year occur in New Mexico. Antibiotics are effective ... . Amazon flex sub same day

Play Plague Inc. Online in Browser. Plague Inc. is a simulation game developed by Miniclip.com and now.gg allows playing game online in your browser. There are many more interesting online games that you can explore here. READ MORE FAQs.Background. There are three types of plague. Most of the sick in 1665-1666 had bubonic plague. This created swellings (buboes) in the lymph nodes found in the armpits, groin and neck. Plague sufferers experienced headaches, vomiting and fever. They had a 30% chance of dying within two weeks. In a plague emergency, CDC and other federal agencies would work closely with state and local partners to coordinate a response. CDC and other federal agencies would respond by: Coordinating activities through the Emergency Operations Center. Communicating information about plague to the public. Providing guidance to healthcare providers ...Black Death. The Black Death (also known as the Pestilence, the Great Mortality or the Plague) [a] was a bubonic plague pandemic occurring in Western Eurasia and North Africa from 1346 to 1353. It is the most fatal pandemic recorded in human history, causing the deaths of 75–200 million people, [1] peaking in Europe from 1347 to 1351.Apr 7, 2020 · Experts believe that the name “Black Plague” was a mistranslation of the Latin word “atra mors” which could mean either “terrible” or “black.”. It was originally estimated that on average, a third of the population of affected areas was wiped out by the plague over its most destructive decade between 1346 and 1353, but other ... Jul 23, 2021 · The plague is treatable in humans and animals if caught and addressed early. CBSN Denver noted that last year, two people in Colorado were confirmed to have contracted the plague, and both survived. The disease is most common in parts of Africa, Asia and South America, but it also occurs in some areas of the western United States. Symptoms can include an abrupt onset of chills, fever, and enlarged, painful lymph nodes (buboes). Most cases of plague resolve with effective treatment, though treatment must be started immediately to avoid life ...Nov 22, 2021 · The Moscow Plague. The Moscow plague hit the earth in 1770. It mainly impacted the Moscow people. And, it was believed to be a replication of the bubonic plague. The plague killed an average of 50 ... The Black Death was a devastating global epidemic of bubonic plague that struck Europe and Asia in the mid-1300s. Explore the facts of the plague, the symptoms it caused and how millions died...What is plague? Plague is a disease caused by Yersinia pestis that affects rodents (e.g., squirrels, prairie dogs, or mice), other mammals (e.g., rabbits or hares), and humans. These bacteria are found in many areas of the world, including the western United States. There are three forms of plague: bubonic (lymph node infection), pneumonic (lung […]The Black Death was a bubonic plague pandemic, which reached England in June 1348. It was the first and most severe manifestation of the second pandemic, caused by Yersinia pestis bacteria. The term Black Death was not used until the late 17th century. Originating in Asia, it spread west along the trade routes across Europe and arrived on the ... Plague: Directed by Nick Kozakis, Kosta Ouzas. With Don Bridges, Cris Cochrane, Tegan Crowley, Liza Dennis. A small group of survivors in post-apocalyptic Australia seek shelter from an infection that has spread like a plague among the human populace.New plague vaccines are in development but are not expected to be commercially available in the immediate future. Page last reviewed: November 27, 2018 Content source: Centers for Disease Control and Prevention , National Center for Emerging and Zoonotic Infectious Diseases (NCEZID) , Division of Vector-Borne Diseases (DVBD)Black Death, pandemic that ravaged Europe between 1347 and 1351, taking a proportionately greater toll of life than any other known epidemic or war up to that time. The Black Death is widely thought to have been the result of plague, caused by infection with the bacterium Yersinia pestis.The bubonic plague was the most commonly seen form during the Black Death, with a mortality rate of 30-75% and symptoms including fever of 38 - 41 °C (101-105 °F), headaches, painful aching joints, nausea and vomiting, and a general feeling of malaise. Of those who contracted the bubonic plague, 4 out of 5 died within eight days.noun. an epidemic disease that causes high mortality; pestilence. an infectious, epidemic disease caused by a bacterium, Yersinia pestis, characterized by fever, chills, and prostration, transmitted to humans from rats by means of the bites of fleas.: Compare bubonic plague, pneumonic plague, septicemic plague.Black Death, pandemic that ravaged Europe between 1347 and 1351, taking a proportionately greater toll of life than any other known epidemic or war up to that time. The Black Death is widely thought to have been the result of plague, caused by infection with the bacterium Yersinia pestis.Plague Inc. is a unique mix of high strategy and terrifyingly realistic simulation with over 700 million games played! Your pathogen has just infected 'Patient Zero'. Now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself.Sep 7, 2023 · Blurbs expose this ecosystem for what it really is: a nepotism-filled system that everyone endures for a chance of “making it” in an impossible industry for most. To borrow a phrase from ... The bubonic plague was the most commonly seen form during the Black Death, with a mortality rate of 30-75% and symptoms including fever of 38 - 41 °C (101-105 °F), headaches, painful aching joints, nausea and vomiting, and a general feeling of malaise. Of those who contracted the bubonic plague, 4 out of 5 died within eight days.Define plague. plague synonyms, plague pronunciation, plague translation, English dictionary definition of plague. ) n. 1. a. A highly infectious epidemic disease ...plague of [sth] n. figurative ( [sth] bad and persistent) serie, ondata nf. Anna has suffered a plague of misfortunes. Anna è stata vittima di una serie di disgrazie. plague [sb/sth] ⇒ vtr. figurative, often passive (afflict) (figurato) flagellare ⇒ vtr. That country has been plagued by misfortune.List of epidemics and pandemics. 17th-century German "plague panel" depicting the triumph of death. Panels of this kind were placed on the walls of houses to warn against the plague. A plague epidemic raged in Augsburg, Bavaria, between 1632 and 1635. This is a list of the largest known epidemics and pandemics caused by an infectious disease.Plague: Directed by Nick Kozakis, Kosta Ouzas. With Don Bridges, Cris Cochrane, Tegan Crowley, Liza Dennis. A small group of survivors in post-apocalyptic Australia seek shelter from an infection that has spread like a plague among the human populace.11 hours ago · Since the Act was enacted in 1966, NHTSA has recalled more than 390 million cars, trucks, buses, recreational vehicles, motorcycles, and mopeds. From 2018 through 2022 there were about 32 million ... Plague is an illness you get from Yersinia pestis bacterium. You usually get the most common form (bubonic plague) from flea bites, but you can get pneumonic plague from someone who’s infected. Plague caused deadly pandemics in the past and still exists in many countries today. You can survive plague if you’re treated with antibiotics quickly.What is plague? Plague is a disease caused by Yersinia pestis that affects rodents (e.g., squirrels, prairie dogs, or mice), other mammals (e.g., rabbits or hares), and humans. These bacteria are found in many areas of the world, including the western United States. There are three forms of plague: bubonic (lymph node infection), pneumonic (lung […]Bubonic plague can advance and spread to the lungs, which is the more severe type of plague called Pneumonic plague. Pneumonic plague – or lung-based plague – is the most virulent form of plague. Incubation can be as short as 24 hours. Any person with pneumonic plague may transmit the disease via droplets to other humans.The Plague Runeword is a Weapon Runeword in Diablo II: Resurrected Patch 2.7 & Ladder Season 4, introduced in the Patch 2.4 Ladder Season 1. In this guide, we will give you quick facts about Plague, strengths and weaknesses, best classes and specs, best Mercenary use, best socketed base items to use to create this Runeword, and hints for farming the necessary Runes.Plague is an infectious disease caused by the bacterium Yersinia pestis. Symptoms include fever, weakness and headache. Usually this begins one to seven days after exposure. There are three forms of plague, each affecting a different part of the body and causing associated symptoms. Experts believe that the name “Black Plague” was a mistranslation of the Latin word “atra mors” which could mean either “terrible” or “black.”. It was originally estimated that on average, a third of the population of affected areas was wiped out by the plague over its most destructive decade between 1346 and 1353, but other ...Plague. Plague, caused by the bacterium Yersinia pestis, is a disease that affects humans and other mammals. People typically get infected after being bitten by a rodent flea that is carrying the bacterium or by handling a plague-infected animal. Although the disease killed millions in Europe during the Middle Ages, antibiotics effectively ...Bubonic plague is one of three types of plague caused by the bacterium Yersinia pestis. [1] One to seven days after exposure to the bacteria, flu-like symptoms develop. [1] These symptoms include fever, headaches, and vomiting, [1] as well as swollen and painful lymph nodes occurring in the area closest to where the bacteria entered the skin. [2]Oct 12, 2016 · The plague laid siege to the city of London several times during the 16th and 17th centuries, most famously between 1665 and 1666. The pestilence first arose in the suburb of St. Giles-in-the ... Plague: Directed by Nick Kozakis, Kosta Ouzas. With Don Bridges, Cris Cochrane, Tegan Crowley, Liza Dennis. A small group of survivors in post-apocalyptic Australia seek shelter from an infection that has spread like a plague among the human populace.Plague. Plague, caused by the bacterium Yersinia pestis, is a disease that affects humans and other mammals. People typically get infected after being bitten by a rodent flea that is carrying the bacterium or by handling a plague-infected animal. Although the disease killed millions in Europe during the Middle Ages, antibiotics effectively ...Septicemic plague can occur as the first symptom of plague or may develop from untreated bubonic plague. This form results from bites of infected fleas or from handling an infected animal. Pneumonic plague: The incubation period of pneumonic plague is usually just 1 to 3 days. Patients develop fever, headache, weakness, and a rapidly developing ...plague: [noun] a disastrous evil or affliction : calamity. a destructively numerous influx or multiplication of a noxious animal : infestation. Sep 4, 2023 · Pneumonic plague affects the lungs and causes symptoms similar to those of severe pneumonia: fever, weakness, and shortness of breath. Fluid fills the lungs and can cause death if untreated. Other symptoms may include insomnia, stupor, a staggering gait, speech disorder, and loss of memory. Septicemic plague is an infection of the blood. Its ... Before covid-19, this was the world’s most recent pandemic, infecting as much as 21 percent of the world’s population. Swine flu was a hodgepodge of several different flu strains that had ...Septicemic plague (Black Death or black plague) symptoms and signs include fever, weakness, abdominal pain, chills, and shock. Tissue bleeding and death may cause the dying tissues to appear black. Pneumonic plague symptoms and signs include characteristic pneumonia symptoms like chest pain, shortness of breath, cough, fever, chills, nausea ...The Plague Disease and Plague as a Bioweapon sections of this Safety and Health Topic provide extensive information on the hazards associated with plague and applicable controls. Additional guidance specific to various types of workers, and associated issues on recognizing and controlling exposure to plague is provided in the following sections ... Plague is an infectious disease caused by the bacterium Yersinia pestis. Symptoms include fever, weakness and headache. Usually this begins one to seven days after exposure. There are three forms of plague, each affecting a different part of the body and causing associated symptoms.The Plague. The first outbreak of plague swept across England in 1348-49. It seems to have travelled across the south in bubonic form during the summer months of 1348, before mutating into the ...History of Plague Epidemics. The plague has afflicted humanity for thousands of years.1, 2, 3 Molecular studies identified the presence of the Y. pestis plague DNA genome in 2 Bronze Age skeletons dated at roughly 3800 years old. 9 In the biblical book 1 Samuel from approximately 1000 BCE, the Philistines experience an outbreak of tumors associated with rodents, which might have been bubonic ...Plagues of Egypt. Scenes from the book of Exodus: The death of the firstborns (including the Pharaoh 's son), and the Israelites leaving Egypt ( Haggadah shel Pesaḥ, 1325–1374 CE, Barcelona via British Library) The Plagues of Egypt, in the account of the book of Exodus, are ten disasters inflicted on Biblical Egypt by the God of Israel in ... Synonyms for PLAGUE: afflict, persecute, torture, besiege, curse, attack, beset, torment; Antonyms of PLAGUE: help, aid, assist, relieve, release, deliver, abet, comfortSep 7, 2023 · Blurbs expose this ecosystem for what it really is: a nepotism-filled system that everyone endures for a chance of “making it” in an impossible industry for most. To borrow a phrase from ... Sep 7, 2023 · Blurbs expose this ecosystem for what it really is: a nepotism-filled system that everyone endures for a chance of “making it” in an impossible industry for most. To borrow a phrase from ... Find 86 ways to say PLAGUE, along with antonyms, related words, and example sentences at Thesaurus.com, the world's most trusted free thesaurus.The bubonic plague was the most commonly seen form during the Black Death, with a mortality rate of 30-75% and symptoms including fever of 38 - 41 °C (101-105 °F), headaches, painful aching joints, nausea and vomiting, and a general feeling of malaise. Of those who contracted the bubonic plague, 4 out of 5 died within eight days. Plague. Plague is an infectious disease of animals and humans caused by a bacterium named Yersinia pestis. People usually get plague from the bite of a rodent flea that is carrying plague bacteria or by handling an infected animal. Although plague is a rare disease, about half of US cases each year occur in New Mexico. Antibiotics are effective ... Plague doctors, or at least images of plague doctors, are having a bit of a cultural moment again, roughly 300 years after their actual heyday. Subscribe to newsletters Subscribe for $39.99/yearPlagues of Egypt. Scenes from the book of Exodus: The death of the firstborns (including the Pharaoh 's son), and the Israelites leaving Egypt ( Haggadah shel Pesaḥ, 1325–1374 CE, Barcelona via British Library) The Plagues of Egypt, in the account of the book of Exodus, are ten disasters inflicted on Biblical Egypt by the God of Israel in ... PLAGUE. Plague is a disease of rodents and their fleas that can be transmitted to humans. Throughout history, plague, often referred to as the " Black Death ," has caused catastrophic pandemics resulting in deaths of tens of millions of persons. The disease is caused by a gram-negative bacterium, Yersinia pestis.Bubonic plague is one of three types of plague caused by the bacterium Yersinia pestis. [1] One to seven days after exposure to the bacteria, flu-like symptoms develop. [1] These symptoms include fever, headaches, and vomiting, [1] as well as swollen and painful lymph nodes occurring in the area closest to where the bacteria entered the skin. [2]The bubonic plague was the most commonly seen form during the Black Death, with a mortality rate of 30-75% and symptoms including fever of 38 - 41 °C (101-105 °F), headaches, painful aching joints, nausea and vomiting, and a general feeling of malaise. Of those who contracted the bubonic plague, 4 out of 5 died within eight days. Aug 29, 2023 · The Latin word also is the source of Old Irish plag (genitive plaige) "plague, pestilence," German Plage, Dutch plaage. Meaning "epidemic that causes many deaths" is from 1540s; specifically in reference to bubonic plague from c. 1600. Modern spelling follows French, which had plague from 15c. Weakened sense of "anything annoying" is from c. 1600. plague meaning: 1. to cause worry, pain, or difficulty to someone or something over a period of time: 2. to annoy…. Learn more.The Plague. The first outbreak of plague swept across England in 1348-49. It seems to have travelled across the south in bubonic form during the summer months of 1348, before mutating into the ...Bubonic plague. This is the most common type. It causes buboes, which are very swollen and painful lymph nodes under the arms, in the neck, or in the groin. Without treatment, the bacteria can ...The plague hits Marseille, Paris and Normandy, and then the strain splits, with one strain moving onto the now-Belgian city of Tournai to the east and the other passing through Calais. and Avignon ...PLAGUE. Plague is a disease of rodents and their fleas that can be transmitted to humans. Throughout history, plague, often referred to as the " Black Death ," has caused catastrophic pandemics resulting in deaths of tens of millions of persons. The disease is caused by a gram-negative bacterium, Yersinia pestis.Mar 28, 2023 · Septicemic plague (Black Death or black plague) symptoms and signs include fever, weakness, abdominal pain, chills, and shock. Tissue bleeding and death may cause the dying tissues to appear black. Pneumonic plague symptoms and signs include characteristic pneumonia symptoms like chest pain, shortness of breath, cough, fever, chills, nausea ... Apr 16, 2020 · The Black Death of 1347-1352 CE is the most infamous plague outbreak of the medieval world, unprecedented and unequaled until the 1918-1919 CE flu pandemic in the modern age. The cause of the plague was unknown and, in accordance with the general understanding of the Middle Ages, was attributed to supernatural forces and, primarily, the will or ... plague n. (infestation of insects or rats) invasion nf. (de moustiques, sauterelles,...) nuée nf. The citizens of Hamlin called on the services of the Pied Piper because of a plague of rats. Les citoyens de la ville de Hamelin ont fait appel au service du joueur de flûte à cause d'une invasion de rats. plague n.Bubonic plague: Humans can come into contact with plague when an infected flea bites a person or when materials that have plague bacteria enter through a break (a cut or sore) in a person's skin. This is the most common form of plague. Pneumonic plague: Humans can come into contact with plague when a person breathes in plague bacteria from the air.Jul 6, 2020 · Bubonic plague, the disease's most common form, refers to telltale buboes—painfully swollen lymph nodes—that appear around the groin, armpit, or neck. The skin sores become black, leading to ... Nov 16, 2022 · Over 80% of United States plague cases have been the bubonic form. In recent decades, an average of seven human plague cases have been reported each year (range: 1–17 cases per year). Plague has occurred in people of all ages (infants up to age 96), though 50% of cases occur in people ages 12–45. It occurs in both men and women, though ... Sep 24, 2020 · History of Plague Epidemics. The plague has afflicted humanity for thousands of years.1, 2, 3 Molecular studies identified the presence of the Y. pestis plague DNA genome in 2 Bronze Age skeletons dated at roughly 3800 years old. 9 In the biblical book 1 Samuel from approximately 1000 BCE, the Philistines experience an outbreak of tumors associated with rodents, which might have been bubonic ... In a plague emergency, CDC and other federal agencies would work closely with state and local partners to coordinate a response. CDC and other federal agencies would respond by: Coordinating activities through the Emergency Operations Center. Communicating information about plague to the public. Providing guidance to healthcare providers ...Play Plague Inc. Online in Browser. Plague Inc. is a simulation game developed by Miniclip.com and now.gg allows playing game online in your browser. There are many more interesting online games that you can explore here. READ MORE FAQs.Bubonic plague: Humans can come into contact with plague when an infected flea bites a person or when materials that have plague bacteria enter through a break (a cut or sore) in a person's skin. This is the most common form of plague. Pneumonic plague: Humans can come into contact with plague when a person breathes in plague bacteria from the air.a serious disease that kills many people, often used to refer to bubonic plague, a very infectious disease caused by bacteria spread mainly by fleas (= small insects that bite) on rats or other animals, that causes swelling, fever, and usually death in humans:Plague. Plague is an infectious disease caused by Yersinia pestis bacteria, usually found in small mammals and their fleas. The disease is transmitted between animals via their fleas and, as it is a zoonotic bacterium, it can also transmit from animals to humans. Humans can be contaminated by the bite of infected fleas, through direct contact ... Methods. CDC developed these guidelines after reviewing existing data on treatment and prophylaxis of plague, collecting and summarizing additional evidence, and gathering input from approximately 90 experts in numerous fields, including infectious diseases, emergency medicine, pharmacology, neonatology, obstetrics and gynecology, geriatrics, microbiology, epidemiology, and crisis standards of ...Pneumonic plague is the most serious form of the disease and the only form that can spread from person to person. As a result of a bioterrorist attack, sick people would likely be seen outside the areas where plague naturally occurs due to the potential for release in other areas and person-to-person spread between close contacts. Plague Inc. is a unique mix of high strategy and terrifyingly realistic simulation with over 700 million games played! Your pathogen has just infected 'Patient Zero'. Now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself.Responding to a Plague Bioterrorism Event. Kettles, buckets, lanterns, and other equipment were used in catching rats during the Public Health Service campaign against the New Orleans plague epidemic of 1914-1920. (Library of Medicine) Page last reviewed: February 7, 2022. Content source: Centers for Disease Control and Prevention, National ...Before covid-19, this was the world’s most recent pandemic, infecting as much as 21 percent of the world’s population. Swine flu was a hodgepodge of several different flu strains that had ...Plague Inc: Evolved is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero' - now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself. Recent Reviews: Overwhelmingly Positive (361)

Plague: Directed by Nick Kozakis, Kosta Ouzas. With Don Bridges, Cris Cochrane, Tegan Crowley, Liza Dennis. A small group of survivors in post-apocalyptic Australia seek shelter from an infection that has spread like a plague among the human populace.. Centre hall truck pulls

plague

Collection. by Mark Cartwright. published on 26 March 2020. Plagues have swept through humanity ever since communities have gathered together in concentrated groups. In this collection of resources, we look at just some of the pandemics that raged throughout Antiquity and the Middle Ages, from the plague that ripped through Athens in the 5th ...The bubonic plague was the most commonly seen form during the Black Death, with a mortality rate of 30-75% and symptoms including fever of 38 - 41 °C (101-105 °F), headaches, painful aching joints, nausea and vomiting, and a general feeling of malaise. Of those who contracted the bubonic plague, 4 out of 5 died within eight days. Plague Inc: Evolved is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero' - now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself. Recent Reviews: Overwhelmingly Positive (361) Plague is an infectious disease caused by the bacteria Yersinia pestis, a zoonotic bacteria, usually found in small mammals and their fleas. It is transmitted between animals from their fleas. Humans can be contaminated by the bite of infected fleas, through direct contact with infected materials or by inhalation.The bubonic plague was the most commonly seen form during the Black Death, with a mortality rate of 30-75% and symptoms including fever of 38 - 41 °C (101-105 °F), headaches, painful aching joints, nausea and vomiting, and a general feeling of malaise. Of those who contracted the bubonic plague, 4 out of 5 died within eight days. Plague Inc. is a unique mix of high strategy and terrifyingly realistic simulation with over 700 million games played! Your pathogen has just infected 'Patient Zero'. Now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself.Pneumonic plague is the most serious form of the disease and the only form that can spread from person to person. As a result of a bioterrorist attack, sick people would likely be seen outside the areas where plague naturally occurs due to the potential for release in other areas and person-to-person spread between close contacts. Plague: Directed by Nick Kozakis, Kosta Ouzas. With Don Bridges, Cris Cochrane, Tegan Crowley, Liza Dennis. A small group of survivors in post-apocalyptic Australia seek shelter from an infection that has spread like a plague among the human populace.Evidence suggests Washtenaw County’s criminal legal system is rife with disparities based on race, and those are among the 65 recommendations of a sprawling new report released on Aug. 31 that ...plague of [sth] n. figurative ( [sth] bad and persistent) ~의 재앙 명. Anna has suffered a plague of misfortunes. 안나는 불운의 재앙을 겪었다. plague [sb/sth] ⇒ vtr. figurative, often passive (afflict) ~에 피해를 주다, ~을 괴롭히다. That country has been plagued by misfortune.The plague is treatable in humans and animals if caught and addressed early. CBSN Denver noted that last year, two people in Colorado were confirmed to have contracted the plague, and both survived.Pneumonic plague is the most serious form of the disease and the only form that can spread from person to person. As a result of a bioterrorist attack, sick people would likely be seen outside the areas where plague naturally occurs due to the potential for release in other areas and person-to-person spread between close contacts.Plague. Plague is an infectious disease of animals and humans caused by a bacterium named Yersinia pestis. People usually get plague from the bite of a rodent flea that is carrying plague bacteria or by handling an infected animal. Although plague is a rare disease, about half of US cases each year occur in New Mexico. Antibiotics are effective ... Pneumonic plague is the most serious form of the disease and the only form that can spread from person to person. As a result of a bioterrorist attack, sick people would likely be seen outside the areas where plague naturally occurs due to the potential for release in other areas and person-to-person spread between close contacts.Aug 29, 2023 · The Latin word also is the source of Old Irish plag (genitive plaige) "plague, pestilence," German Plage, Dutch plaage. Meaning "epidemic that causes many deaths" is from 1540s; specifically in reference to bubonic plague from c. 1600. Modern spelling follows French, which had plague from 15c. Weakened sense of "anything annoying" is from c. 1600. The Crossword Solver found 60 answers to "plague", 4 letters crossword clue. The Crossword Solver finds answers to classic crosswords and cryptic crossword puzzles. Enter the length or pattern for better results. Click the answer to find similar crossword clues . Enter a Crossword Clue..

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